Abu dhabi: A team of scientists at Washington University School of Medicine has identified a neural mechanism capable of switching off chronic neuropathic pain caused by nerve damage.

According to Emirates News Agency, the discovery centers on mu opioid receptors located within the locus coeruleus, a brain region that helps regulate stress and alertness. Researchers found that activating these specific receptors functions as a molecular brake, suppressing hyperactive pain pathways and reversing hypersensitivity.

By directly targeting localized receptors in the brain's pain center rather than administering systemic opioids across the entire body, this approach promises to yield highly targeted therapies that relieve severe pain while eliminating side effects and addiction risks.